Mnohopočetný myelóm

Nevieme prečo tento zvláštny druh rakoviny vzniká, neviem ani to, ako mu možno predísť. Vieme ho však liečiť a zabezpečiť si aj s tak vážnym ochorením dlhý a kvalitný život.


Neprehliadajme to, čo dokážeme riešiť!

Jedným z ochorení, ktoré postihuje najmä starších ľudí a spôsobuje vrásky lekárom po celej Európe, je ochorenie s názvom mnohopočetný myelóm.
Nevieme prečo tento zvláštny druh rakoviny vzniká, neviem ani to, ako mu možno predísť. Vieme ho však liečiť a zabezpečiť si aj s tak vážnym ochorením dlhý a kvalitný život.
To čo viacerých odborníkov trápi, je fakt, že verejnosť a mnohokrát aj lekári prvého kontaktu ochorenie prehliadajú a k pomoci dochádza neraz pozde. Aj preto sa rozhodli spojiť sily a tento celoeurópsky zdravotnícky problém riešiť.


Čo je to mnohopočetný myelóm a prečo o je potrebné o ňom vedieť?

Mnohopočetný myelóm je zriedkavý, predstavuje zhruba 1% všetkých rakovín. Avšak toto číslo mu nedáva dôvod na to, aby sa mu venovala menšia pozornosť. Podľa informácií Slovenskej myelómovej spoločnosti v súčasnosti týmto ochorením trpí 84 000 ľudí v Európe, pričom až 600 prípadov ochorenia pochádza zo Slovenska. Odborníci sa domnievajú, že toto číslo môže byť v skutočnosti oveľa vyššie. Zdôrazňujú, že za jeho neskorým odhalením je práve nedostatočná informovanosť o jeho existencii a možných príznakoch. Aj preto bol spustený program, ktorý má zabezpečiť väčšiu informovanosť nie len lekárov prvého kontaktu, ale i širokej verejnosti.


MUDr. Katarína Masárová - 
hematologička z Univerzitnej nemocnice Bratislava - Nemocnica sv. Cyrila a Metoda

„Mnohopočetný myelóm je zhubné lymfoproliferatívne ochorenie. Mnohí si jeho pomenovanie uľahčujú a jednoducho ho len zaradia medzi nádorové ochorenie kostnej drene. Mnohopočetný myelóm je však o niečo špecifickejšie ochorenie, pri ktorom sa určitý druh bielych krviniek, ktoré voláme plazmatické bunky, začnú v kostnej dreni množiť vo veľkom počte a tým pádom sa začnú vytvárať osteolytické ložiská  v kostiach“, začína vysvetľovať zákernosť choroby hematologička MUDr. Katarína Masárová.

Na rozdiel od mnohých iných druhov rakoviny, mnohopočetný myelóm nemá formu hrčky alebo nádoru. Namiesto toho sa myelómové bunky vytvárajú a šíria práve v rámci kostnej drene a čo je zaujímavé, ochorenie postihuje prevažne staršie generácie. „Najviac pacientov máme vo veku 55-70 rokov, ale výnimkou nie sú ani štyridsiatnici, ba dokonca evidujeme aj malú skupinku tridsiatnikov“, potvrdzuje európske štatistiky slovenská odborníčka.


Symptómy

Medzi najčastejšie symptómy a vedľajšie účinky mnohopočetného myelómu patria bolesť kostí, zlomeniny kostí, únava, opakované alebo pretrvávajúce infekcie, zápaly, poškodenie obličiekhyperkalcémia. Tohto ochorenia sa nemožno úplne zbaviť, no ako hovorí MUDr. Masárová, dá sa s ním naučiť žiť. „Mnohopočetný myelóm sa ráta medzi chronické, nevyliečiteľné ochorenia, ale na druhej strane dobre liečiteľné. To znamená, že dobre reaguje na liečbu. Choroba sa môže vracať, ale pacienti s ňou môžu prežiť skutočne kvalitný život ešte ďalších dvadsať rokov“, ubezpečuje Katarína Masárová.

V súčasnosti sa tento celoeurópsky zdravotnícky problém dostal do popredia a prijímajú sa potrebné riešenia. Slovenská myelómová spoločnosť a teda i množstvo slovenských odborníkov a lekárov koná po celom Slovensku aj pre obvodných lekárov raz do mesiaca prednášky, kde sa dozvedia všetky potrebné informácie, s ktorými pacient môže prísť a ktoré môžu pomôcť k včasnému odhaleniu mnohopočetného myelómu. „Stávalo sa, že k nám prišiel pacient už na vozíčku. Tvrdil, že prišiel k obvodnému lekárovi s bolesťami chrbtice a odchádzal z vyšetrenia s vyhodnotením, že veď koho dnes nebolí chrbtica,“ spomína s pohoršením vyhľadávaná hematologička a vzápätí potvrdzuje, že potreba väčšej informovanosti nie len lekárov prvého kontaktu, ale i širokej verejnosti sa ukázala pri liečbe mnohopočetného myelómu ako kľúčová: „Po tom, ako sa rozbehlo toto vzdelávanie, narástol aj prísun pacientov, ktorým bolo možne včas podať potrebnú liečbu. Tí, ktorým bola diagnóza stanovená už v neskoršom štádiu, to znamená, že už boli na vozíku alebo na lôžku, sa majú dnes dobre, znovu chodia, poniektorí dokonca športujú,“ dodáva Katarína Masárová. 

Základné informácie o ochorení:

• Mnohopočetný myelóm je zriedkavý druh rakoviny kostnej drene prameniaci z plazmatických buniek v kostnej dreni.

• Nie je vyliečiteľný. Cieľom liečby je zabrániť rozvoju choroby, navodiť remisiu a zlepšiť kvalitu života.

• Obvykle ním trpia ľudia starší ako 60 rokov a postihuje viac mužov ako ženy.

• Najčastejšími symptómami a vedľajšími účinkami sú bolesť kostí, zlomeniny kostí, únava, opakované alebo pretrvávajúce infekcie, poškodenie obličiek a hyperkalcémia, čiže zvýšená hladina vápnika v krvi.

Viac informácií o ochorení pre laickú verejnosť, pacientov a ich rodinných príslušníkov, taktiež pre lekárov sa možno dočítať na www.myelom.sk

Foto:  MUDr. Katarína Masárová

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    substitute remedy outweigh the drawbacks. It requires caution, as testosterone can enhance the
    chance of atrial fibrillation. In scientific
    research, we see that men over 65 receiving testosterone might experience worsened cardiac well being
    in the brief term. Nevertheless, long-term use improves cardiac outcomes and reduces the likelihood of mortality (9).

    Anavar will worsen testosterone suppression post-cycle, requiring a
    more superior PCT in comparability with a
    testosterone-only cycle. However, our testing exhibits that Anavar’s
    antagonist results on testosterone are delicate in comparison with different anabolic steroids.


    Moreover, Anavar isn't aromatized by the body, so it won't convert into
    estrogen. This makes it a good selection for men who're concerned concerning
    the improvement of man breasts (gynecomastia).
    If you're figuring out more than thrice per week, we
    recommend starting at the decrease end of the dosage range.
    If you're working out thrice per week or much less, you can start on the greater end of
    the dosage range. If you're new to using steroids, we recommend starting on the lower
    end of the dosage range. If you've used steroids earlier than, you can begin on the larger finish of the dosage range.
    Anavar and Winstrol are fairly related, with them both being efficient oral, chopping steroids.

    However, that might be extra of a sophisticated strategy that
    you’d desire a specific reason to comply with.

    Most customers might be satisfied with the standard testosterone major compound.
    Masteron won’t offer you estrogen ache and can lead
    to increased free testosterone, with customers usually reporting enhanced libido in consequence.

    On the opposite hand, Masteron does have some androgenic downsides, so hair loss
    and attainable prostate growth may be issues, especially when using Masteron for a longer
    term. It simply means you need to listen to the right TYPES of steroids
    to use for what you’re attempting to realize.

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