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Bezbolestnou prevenciou k zdraviu

Napísal Michaela Conzarová 16. december 2024

Slovensko je krajinou s druhým najväčším výskytom  rakoviny  hrubého čreva a konečníka v Európe, v úmrtnosti je však na  špici rebríčka. Mnohí ľudia majú  strach absolvovať kolonoskopiu, hoci patrí k prevencii... 

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Na zdravotníckom trhu sa objavila prevratná metóda formou testu Colotest, ktorá je neinvazívna a bezbolestná. Je to pokrok v diagnostike hrubého čreva  aj konečníka a test dostal meno Colotest. O prelomovej novinke  som sa porozprávala  s MVDr.  Sandrou Kováčovou-Kapciovou, produktovou špecialistkou z firmy Zentya.

femme: Akým spôsobom sa môžu potenciálni záujemcovia dostať k testu Colotest?

MVDr. Sandra Kováčová Kapciová:  Pacienti môžu dostať informáciu u svojho všeobecného lekára a taktiež aj z internetu priamo na našej stránke www.colotect.sk , alebo prostredníctvom Facebooku. Mali sme publikované aj rôzne články odkiaľ sa tiež mali možnosť o teste dozvedieť.

femme: Skúste nám objasniť, aké benefity prináša test Colotest a čo nám výsledky prezradia?

MVDr. Sandra Kováčová Kapciová:  Colotest je neinvazívny skríningový DNA test na diagnostiku kolorektálneho karcinómu, takže podá pacientovi informáciu o tom či sa uňho vyskytujú karcinogénne zmeny, ale čo je najväčšou výhodou tohto testu je to, že dokáže detegovať už tie najmenšie zmeny na sliznici čreva. Vďaka svojej vysokej citlivosti zachytí aj predrakovinové štádia ako sú napríklad polypy. Najväčší prínos tohto testu je práve to, že odhalí prekancerózne zmeny, ktoré ešte nemusia byť nebezpečné a po absolvovaní kolonoskopie sa odstránia a pacient je následne bez ďalšej liečby

femme: Ako prebieha celý proces od zabezpečenia testu k výsledku?

MVDr. Sandra Kováčová Kapciová:   Kto má záujem o test,  môže si ho objednať cez našu webovú stránku, následne mu test zašleme poštou na jeho uvedenú adresu.  Vzorku stolice si odoberie klient podľa toho, kedy mu to najviac vyhovuje. Potom nás kontaktuje a my mu zabezpečíme kuriéra, ktorý od neho vzorku prevezme a zašle do genetického laboratória Medgen, ktoré sídli v Bratislave. Výsledky klientovi zasielame emailom do 14 pracovných dní, tiež zabezpečujeme aj telefonickú konzultáciu.

femme: Od akého veku je vhodný Colotest?

MVDr. Sandra Kováčová Kapciová:   Odporúčanie je od 40. - 45. roku života, keďže vtedy je výskyt kolorektálneho karcinómu vyšší, ale samozrejme môže ho absolvovať ktokoľvek, komu záleží na jeho zdraví alebo má nejaké pochybnosti.

femme: Akú máte odozvu na test a od koho prichádza?

MVDr. Sandra Kováčová Kapciová:   Spätná väzba prichádza hlavne od pacientov, ktorí mali pozitívny výsledok a následne absolvovali kolonoskopiu, tak nás informujú o výsledku kolonoskopického vyšetrenia.

femme: Vzorky od klientov k vám chodia z celého Slovenska, alebo máte aj v iných mestách pobočky?

MVDr. Sandra Kováčová Kapciová:   Keďže klientom test zasielame poštou a odvoz vzorky zabezpečuje kuriér, fungujeme v rámci celého Slovenska. Klient nemusí nikam chodiť, stačí keď nás kontaktuje telefonicky alebo prostredníctvom našej webovej stránky a my všetko zabezpečíme.

femme: Ak je negatívny test, človek sa uspokojí, keď pozitívny, aké sú jeho ďalšie kroky?

MVDr. Sandra Kováčová Kapciová:  Ak je test negatívny, odporúča sa zopakovať ho po 2. -  3. rokoch a ak je pozitívny, tak je potrebné absolvovať kolonoskopiu.

femme: Dajú  sa pomocou Colotestu zistiť polypy v črevách?

MVDr. Sandra Kováčová Kapciová:   Áno, ako som už spomínala, Colotest deteguje aj včasné vývojové štádia, medzi ktoré patria polypy.

femme: Ak má niekto hemoroidy, pre neho je asi vhodnejší Colotest ako kolonoskopia...

MVDr. Sandra Kováčová Kapciová:   Pri hemoroidoch je vhodný Colotest, hlavne u pacientov, ktorí mali spravený test na okultné krvácanie čo sa robí v rámci prevencie u všeobecného lekára, ten zachytáva krv v stolici. Práve pri hemoroidoch,  potom môže byť falošne pozitívny výsledok a veľakrát si vtedy pacienti povedia, že krv v stolici sa vyskytla kvôli hemoroidom a odmietnu kolonoskopiu. V takom prípade je vhodné absolvovať Colotest, aby si bol pacient naozaj istý a následne podnikol ďalšie kroky.

femme: Test je pomerne drahý, čo všetko predstavuje jeho vyhotovenie?

MVDr. Sandra Kováčová Kapciová:  Ide o zložité genetické vyšetrenie, ktoré poskytuje informáciu až o troch génových biomarkeroch. Robí sa izolácia DNA a niekoľko stupňová analýza vzorky. Sleduje sa abnormálna metylácia DNA, ktorá je jednou z prvých molekulárnych zmien, ktoré sa vyskytujú počas karcinogenézy.

femme: Na záver, aká  je spoľahlivosť testu?

MVDr. Sandra Kováčová Kapciová:     Spoľahlivosť testu je 93%, pričom spoľahlivosť kolonoskopie je 95%.

femme:: Ponúkate aj iné testy?

MVDr. Sandra Kováčová Kapciová:   Naša spoločnosť ponúka niekoľko skríningových genetických testov ako sú napríklad prenatálne testy Nifty. Genetické testy zamerané na rakovinové predispozície a taktiež aj priamo pre onkologických pacientov testy vyhodnocujúce najvhodnejšiu liečbu, či mnoho ďalších, o ktorých sa u nás môžu pacienti informovať.

Viac informácii nájdete aj na videu:

13 komentárov

  • Komentár https://pmsbio.link/arlenuhr1 %PM, %08 %940 %2025 %21:%apr napísal https://pmsbio.link/arlenuhr1

    This is because Anavar can suppress pure testosterone manufacturing, and mixing it
    with exogenous testosterone may help mitigate this impact.

    However, it’s necessary to do not forget
    that adding testosterone to the mix can enhance the risk of unwanted effects, particularly if the dosage is just too
    excessive. If you’re an endurance athlete looking to improve your performance,
    Anavar can supply a number of advantages. It’s a mild steroid that may enhance your cardiovascular
    endurance, increase oxygen delivery to your muscles, and boost your
    red blood cell count. The recommended Anavar dosage for powerlifters is between 20 to 80mg per day, depending on expertise stage, goals,
    and body weight. It is advisable to begin with a lower dose and
    steadily enhance it to the desired level to allow the physique to adapt to the
    results of the drug.
    A lady ought to discontinue her cycle if she begins to experience any unwanted symptoms.
    Body composition and metabolic price additional affect Anavar’s pharmacokinetics.
    Individuals with greater lean physique mass might have adjusted doses for adequate anabolic stimulation, while metabolic fee variations affect drug clearance.


    There’s no means around the fact that Winstrol goes to suppress your natural testosterone manufacturing.
    It is identified as one of the more suppressive steroids, although not the worst by any means.

    Some individuals will have no zits on Winstrol, and
    some will see severe flare-ups and increased oily pores
    and skin. This is another genetically dependent facet impact, though you'll be able to
    try to take measures to mitigate it somewhat by preserving a clean skin regime.

    Androgenic unwanted effects are possible with Winstrol, however
    these will influence everybody differently.
    PCT is a must-do after using Winstrol to get your testosterone
    perform back on observe. Following common sense guidelines may even help
    shield your liver throughout a Winstrol cycle – keep away from all alcohol and
    try not to use any medicines except needed, as many are
    also liver-toxic. Regardless Of injectable Winny’s longer half-life, it could possibly
    still deliver results sooner than the oral model. The main purpose is the upper bioavailability and absorption of Winstrol Depot vs.
    Oral. In The End, your alternative between the two will come down as to if you
    possibly can handle the injection pain and discomfort of Winstrol Depot versus the convenience of popping a pill.

    Sometimes objects usage aren't protected whenever you use them with certain other items and food.
    By following these tips, you can improve your probabilities of buying Anavar safely
    and obtaining a genuine, high-quality product.
    This is a low dose, but every further milligram a feminine takes of Winny does make an enormous
    difference and runs the risk of taking you from a tolerable cycle to one the place virilization starts
    to creep in. Ladies will almost solely use Winstrol in oral form only as a outcome of only very low doses are used, and this has a half-life of
    about 9 hours. You would possibly choose to either take your complete dosage once daily or split it in two
    each day.
    Nonetheless, it’s important to take a glance at what dosage
    they’ve used so you can decide how the dose would possibly affect your outcomes and (lack of) side effects.
    It’s fun to check out before and after photos of people who’ve
    used Anavar, however this tells us nothing
    about any positive aspects in strength they’ve experienced
    on the cycle. Females naturally produce small amounts of testosterone, but when utilizing steroids, this powerful androgen can shortly bring about
    an entire host of undesirable side effects for females.

    Bodybuilders commonly purchase testing kits, enabling them to determine if their Anavar product is authentic.
    Our staff additionally utilizes purity checks to see if doses have been decreased.
    I’m fairly happy with my results thus far, contemplating where I started.

    When Anavar was initially launched in the marketplace, a basic dose of 5–10 mg per day was common. Nonetheless, athletes
    and bodybuilders now usually take 15–25 mg per day.
    We find that when bodybuilders administer Anavar, they
    usually expertise a rise in well-being, confidence, motivation,
    and aggression. This is due to exogenous testosterone supplementation; nevertheless, as quickly as a cycle finishes, users often expertise
    fatigue and reduced libido. Anavar causes significant intracellular water
    retention, resulting in continually full and pumped muscular
    tissues throughout the day. Such muscle fullness, mixed with Anavar’s diuretic
    properties, may find yourself in more distinguished vascularity.

    Research has proven anabolic steroids enhance sprint pace in rats by as much as 29% (14).

    It may enhance the chance of bleeding if taken with blood thinners like warfarin. If combined with different steroids,
    the probabilities of unwanted aspect effects, including liver injury, rise significantly.
    Anavar also can impression blood sugar levels, so these with diabetes ought to
    exercise warning.
    Combining Anavar with different steroids or performance-enhancing drugs increases the risk of dangerous unwanted side effects.
    It’s additionally clever to keep away from high-fat diets that can additional disrupt cholesterol levels.

    Lastly, keep away from extended use to attenuate the risk of long-term harm to your physique.

  • Komentár www.elzse.com %PM, %08 %938 %2025 %21:%apr napísal www.elzse.com

    Testosterone may also suppress endogenous testosterone levels, inflicting
    potential testicular atrophy (shrinkage). Thus, at the end
    of any cycle, at all times ensure to run a correct post-cycle remedy that aids within the recovery
    of pure hormone production. We have found hCG to be specifically effective in treating testicular atrophy.
    Being the primary, naturally occurring male hormone, testosterone is
    one of the mostly used anabolic steroids among bodybuilders.
    When used for efficiency enhancement or bodybuilding, individuals might use higher
    doses, however it’s crucial to notice that growing the dosage additionally increases the risk of side effects.
    It’s typically really helpful to begin with the
    bottom effective dose and progressively titrate upward while carefully
    monitoring for any adverse reactions. Anavar (oxandrolone) is often utilized in bodybuilding
    and fitness circles for its potential to promote the event of lean muscle mass.


    Whereas Anavar has gentle natural testosterone suppression results, it hardly ever totally suppresses or even suppresses at
    half the natural levels. Therefore, the decrease in SHBG continues to be extremely useful regardless of your testosterone levels when utilizing this steroid.
    As with many anabolic steroids there is the risk of creating masculine traits similar to deeper voice, clitoral enlargement, etc.

    However as a result of Anavar’s low androgenic effects and low dosages required for
    leads to women a correctly monitored routine is low in threat and heavy in rewards making it a favorite amongst women. Anavar (Oxandrolone)
    is among the hottest oral steroids at present, primarily because of being well tolerated by
    women and men.
    This detailed information will provide you with complete insights into the vital thing features of Anavar,
    a powerful anabolic steroid that includes 10 mg of Oxandrolone in every of its 100 tablets.
    Anavar works better with dietary changes and strict workouts that entail weight lifting and cardio.
    Through its use, you presumably can handle unnecessary deposition of fat for those,
    leaner, dry gains. Taking under consideration the proscribing ability to endure steroids, ladies shouldn’t
    settle for in excess of 5 mg/day within the primary week.

    We have not observed Anvarol inflicting any side effects, although it's possible for
    individuals to experience minor reactions.
    A liver support supplement is crucial when stacking Anavar with different hepatotoxic orals, such as Winstrol, Anadrol,
    or Dianabol. Nonetheless, such steroid combos usually are
    not advised as the chance of hepatic injury or other opposed results
    remains.
    Anvarol is greatest suited to males or women who want to
    cut back their body fat proportion, whilst concurrently rising muscle tone and
    building lean muscle. These outcomes are typical of Anavar’s effects;
    nonetheless, if users eat in a calorie surplus, fats loss is prone to
    be less than these illustrated above. Thus, food regimen stays an important consider figuring out physique composition on Anavar.

    Our female sufferers have reported feeling depressed and have experienced low libido upon cycle cessation.
    Dave Crosland, the founder of Crosland’s Hurt Reduction Providers,
    has also discovered testosterone and estrogen ranges to
    be poor in females post-Anavar (24). When Anavar (oxandrolone) was first produced,
    it was authorized to buy for bodybuilding purposes.
    Medical Doctors would prescribe it to folks wanting bigger muscle tissue, extra
    power, or to burn extra fat. Testosterone ranges
    sometimes get well one to 4 months after Anavar cycle cessation.
    An efficient PCT protocol can accelerate the restoration of
    endogenous testosterone. Anavar causes significant intracellular water retention, leading to continually full and pumped muscles throughout the day.

    Others, nevertheless, employ anabolic steroids for bodybuilding and efficiency enhancement.
    Anavar can also cause masculinization in girls; nonetheless,
    we do not typically observe this in therapeutic doses. Nevertheless, excessive dosages or combining Anavar
    with different anabolic steroids such as Winstrol increases the chance of masculinization. A user’s outcomes
    on Anavar will depend upon their cycle, dose, genetics,
    diet, and coaching routines. Nonetheless, we see novices generally gaining
    kilos of muscle mass and 7 kilos of fats loss from a 4- to 6-week cycle.

    On the opposite hand, endurance athletes may profit extra from a decrease dosage
    to enhance stamina and cardiovascular endurance.

    Nonetheless, with Anavar’s fat-burning effects and muscle positive aspects being retained post-cycle, there is not an excellent need for most people to utilize Anavar all year round.

    We discover that if junk meals are consumed throughout a cycle, sodium ranges will rise, inflicting water retention. This can inhibit Anavar’s diuretic
    results, inflicting the muscles to seem increasingly smooth
    and reduce muscle definition, striations, and vascularity.
    However, if a person predominantly wants to burn fat on Anavar, then a small calorie deficit can be carried out to speed up fats loss while aiding muscle retention. Cardiovascular
    exercise, or HIIT (high-intensity interval training), may be utilized to accelerate a user’s metabolism while offering cardiac advantages.

    Anadrol is presumably the worst steroid for blood stress, causing hefty rises due to its disastrous
    impression on HDL cholesterol levels. This is because
    of it stimulating hepatic lipase, an enzyme responsible for decreasing good ldl cholesterol (HDL), which prevents
    clogging of the arteries. Like trenbolone acetate,
    Anadrol is fast-acting, so gains could be noticed in just some days following
    the first dose. As we navigate the riveting landscape of bodybuilding, it’s clear that Anavar,
    also referred to as Oxandrolone, could be a vital ally.
    With its versatility and apparent mild touch in comparability with different steroids,
    it’s evident why each men and women undertake it to
    reinforce their health progress.
    About 2-3 weeks in, customers may begin to observe increased energy and a more defined muscle look.
    Nonetheless, this shouldn't be conflated with a drastic rise in muscle mass.

    The true energy of Oxandrolone lies in boosting fats loss, promoting lean muscle preservation and improvement, and improving muscle hardness
    and density. Shunning away the undesired water retention and making the muscle tissue look
    exhausting and dry is a most well-liked alternative for
    cutting cycles. It amps-up energy, even whereas you’re on a low-calorie food plan, and helps you attain that onerous, vascular appearance.
    It further helps muscle development on a smaller scale than different
    steroids, making it a favorite amongst girls and novices.
    Anavar, typically talked about beneath the generic name Oxandrolone,
    holds a well-deserved reputation as one of the mildest
    anabolic steroids.
    Kidney and liver function ought to be unaffected by Primo, and it shouldn’t impact cholesterol levels either.
    Primo is most suited for recomp and cutting, although it has its place in lean bulk
    cycles, as I beforehand mentioned. Therefore, your results come without the bloated look attributable to water retention, which is important for
    a slicing cycle, particularly for competitors.
    However even more so, they both include the same ester attached,
    to permit them to conveniently be mixed and brought all
    inside one single injection. Very low doses of Primo won’t have you
    gaining much or any mass in any respect, however that’s not likely to be your aim if
    you’re starting at a low dose.
    In all however the most excessive circumstances, girls wanting to attain maximum
    leanness will give consideration to getting to 10%-15%
    physique fat. However Anavar isn’t simply great for fat loss
    for ladies, but much more so for sustainable and aesthetically pleasing
    lean positive aspects with no or minimal unwanted effects.
    These could be a few of the most debilitating and physique-ruining
    unwanted side effects of steroid use and include bloating or
    water retention and gynecomastia. You can expect nice dry features without
    estrogenic side effects unless you embrace other aromatizing steroids in your Anavar
    stack. All of those stacks will require a post-cycle therapy protocol afterward.
    A normal PCT is Clomid at 100mg day by day, starting two weeks after
    your last dose. Stacking Anavar will nearly completely be for slicing and recomposition cycles for male users.

  • Komentár git.defcon-nn.ru %PM, %24 %841 %2025 %19:%mar napísal git.defcon-nn.ru

    Make certain you understand how to stabilize your again earlier than adding
    good mornings to your routine. This train carries a
    excessive danger of harm and may damage your spine if executed with dangerous type.
    Most accidents are probably to occur when the torso is
    parallel to the floor.
    Squats are undoubtedly the king of lower-body power coaching, however different contenders are value considering when it
    comes to constructing severe measurement. That mentioned, some individuals take to deadlifting faster than others, and a few by no means
    look or feel comfortable when performing this
    motion. In contrast, most of my trainees become familiar with again extensions almost right away; it’s very much an immediate
    gratification train. Deadlifts are best categorized as a hip hinge
    exercise, that means that a lot of the motion comes from the flexion and extension of the hip joint.

    While your knees do move, their vary of movement is small compared to
    the hip. The kettlebell Romanian deadlift includes hinging at
    the hips to lower kettlebells in course of the ground
    whereas sustaining a slight knee bend, primarily focusing on the hamstrings and
    glutes.
    For athletes exterior of the iron sports, the single-leg deadlift
    does a greater job getting ready the physique
    in your sport. The hip, lumbo-pelvic advanced, and core need to work as a
    unit to keep you from falling whereas generating force. This
    is exactly what you need when running, altering directions, and performing the basic athletic movements.
    This isolation motion may help you construct a stronger again and hamstrings, leading to a decrease danger of injuries.

    The dumbbell Romanian deadlift entails hinging on the hips to decrease dumbbells towards the ground whereas sustaining a slight knee bend.
    The barbell hip thrust includes lifting the hips off the floor whereas a barbell
    rests on the hips, primarily targeting the glutes, hamstrings, and lower back.
    The barbell Romanian deadlift entails hinging on the hips to lower a loaded barbell towards the ground with out bending the knees.

    My reasoning is that, from my understanding, the higher back/traps reply greatest to
    heavy loads. Doing rack pulls permits larger weight
    to be lifted than with deadlifts and subsequently provides greater higher
    back activation. On the other hand RDLs are high rep/low weight and provide higher posterior chain activation than deadlifts
    alone.
    Try pulling into a back lever from the underside up and inform me
    it doesn’t feel as onerous as deadlifting a bar with twice your
    bodyweight. Additionally, follow the precise actions required for every event to enhance
    your technique and kind. With constant training and practice,
    you'll find a way to enhance your efficiency in the ACFT alternate occasions and obtain your
    required rating. No, it is not strictly necessary to perform deadlifts to construct energy or muscle.

    If you really need to prepare your grip even more, you could consider
    doing deadlifts with an axle bar. These differences in comparison with the muscular tissues worked in a farmer’s walk can be each advantages or downsides
    depending on your coaching goals and personal situation. Deadlifts undoubtedly don't have
    the very same focus because the farmer’s stroll but
    there are some necessary commonalities.
    The decrease the peak, the extra your glutes and hamstrings shall be in focus.
    The higher the height, the extra your again might be used,
    so select a top that aligns with no matter your abilities/goals are.
    When the rack is on the desired height and you’re standing along with your ft
    shoulder width aside, place the bar on it and bend down as you hinge forward on the hips
    to grasp it. Then hold it along with your palms in an overhand grip and your palms also shoulder-width aside.