Vytlačiť túto stránku

Netušil, že má len jednu obličku, ani to, že mu zlyháva. Dnes má pre všetkých silný odkaz

Napísal SK 10. marec 2023

Do svojej osemnástky žil Sven Behring život bežného chalana. Študoval, športoval, užíval si mladosť. Až kým nešiel na kontrolu k lekárovi. Ten zistil, že mu chýba jedna oblička. O pár rokov neskôr mu aj tá začala zlyhávať, no on o tom ani len netušil.

1_sven_behring

„Zrazu si naplno uvedomíte, čo znamená žiť,“ hovorí Sven o chvíľach, ktoré mu preorganizovali rebríček hodnôt. Foto: archív S.B.

Sven Behring sa narodil v susednom Česku, odkiaľ je aj jeho maminka. Otec pochádza z Nemecka, preto má toto netradičné meno. Vyrastal však v Karlových Varoch a po vysokej škole sa presťahoval do Plzne, kde žije dodnes. Pracovne však chodí aj na Slovensko. Narodil sa len s jednou obličkou, no keďže sa v tom čase ešte nerobil taký skríning ako dnes, na túto anomáliu sa prišlo, až keď mal osemnásť rokov. „Pôvodne som išiel k urológovi s drobným problémom a pri tejto príležitosti sa zistilo, že mám iba jednu obličku. Lekári ma však uistili, že sa s tým dá plnohodnotne žiť, takže som to v tom veku nejako neprežíval,“ spomína sympatický štyridsiatnik z Plzne na prvé zlomové obdobie v jeho živote.

Náhoda? Šťastie? Asi oboje

To druhé prišlo po 25 rokoch. Svenov život prebiehal bez obmedzení, stal sa otcom dvoch krásnych dievčat. Trochu sa obával, či budú jeho dcéry v poriadku, no našťastie sú obe úplne zdravé. V lete minulého roka mu však do života vošla ďalšia kľúčová náhoda. Keďže Sven pracuje v medicínskej oblasti, stretáva sa tu s rôznymi informáciami. „Zaregistroval som, že mám nárok na preventívne vyšetrenie obličiek. Ja som ten typ pacienta, ktorý nejde k lekárovi, až kým naozaj nemusí. Preventívne prehliadky som teda dlhodobo ignoroval,“ priznáva Sven a dodáva: „Táto informácia ma však oslovila a tak som si dal v auguste svoju obličku vyšetriť. Nemal som žiadne príznaky, nič ma nebolelo, ani vo sne by mi nenapadlo, že na preventívku idem vlastne o päť minút dvanásť.“ Štyridsaťštyri ročný muž pritom nemal žiadne komplikácie, ktoré by na ochorenie poukazovali. Nefajčí, nepije tvrdý alkohol, snaží sa dodržiavať zdravú životosprávu. 

Uvedomil si vlastnú smrteľnosť

Lekár Svenovi oznámil, že jeho jediná oblička postupne zlyháva. „Konkrétne mi diagnostikoval chronické progresívne ochorenie obličiek v stredne pokročilom štádiu. Hneď na to som sa dozvedel, že tento stav je nezvratný, ale jeho postup dokážeme spomaliť,  dokážeme mať ochorenie pod kontrolou. Samozrejme, že som sa sústredil na tú horšiu časť informácie. Vtedy som si uvedomil vlastnú smrteľnosť. Kým sme zdraví, ani nám nenapadne, že by to mohlo byť inak. Moja diagnóza mi zmenila hodnotový rebríček. Uvedomil som si, že nebyť tejto preventívky, je vysoko pravdepodobné, že by som časom skončil na dialýze,“ delí sa o svoje myšlienky muž, ktorý môže hovoriť o šťastí v nešťastí.

2_sven_behring

Svenova priateľka je mu veľkou oporou. Foto: archív S.B.

Choďte na preventívky, kým sú zadarmo

Svenovi nasadili liečbu a stal sa jedným z prvých pacientov liečených novým liekom, ktorý bol predtým určený len pre diabetikov. Preto otec dvoch dievčatiek dnes rozpráva svoj príbeh verejne a verí, že ním motivuje ľudí, aby chodili na pravidelné preventívne prehliadky. „Nádej, že sa moja jediná oblička vylieči, je mizivá. Veľkým úspechom bude, ak sa zhoršovanie môjho ochorenia zastaví, alebo aspoň zabrzdí. Tajne dúfam, že sa ochorenie podarilo odhaliť relatívne včas a budem vďačný za každý rok, ktorý prežijem naplno ako doposiaľ,“ vyznáva sa tento sympaťák.

Otestujte sa, či aj vám hrozí chronické ochorenie obličiek na www.vysetrioblicky.sk

Čo je chronické ochorenie obličiek?

Chronické ochorenie obličiek je zdĺhavý a pomalý proces, počas ktorého obličky postupne strácajú svoju funkciu. „Obličky môžu pracovať len na 10 percent bez toho, aby sme pociťovali akékoľvek príznaky. V tom je skrytá zákernosť tohto ochorenia. Vysoko rizikoví sú najmä diabetici, osoby s vysokým krvným tlakom, kardiovaskulárnymi ochoreniami, pozitívnou rodinnou anamnézou, fajčiari a starší ako 60 rokov. No ochorenie čoraz častejšie postihuje už aj mladšie ročníky,“ upozorňuje doc. MUDr. Martin Demeš, PhD., MPH, hlavný odborník pre nefrológiu na Slovensku.

Chronické ochorenie obličiek je možné už vo včasnom štádiu odhaliť pri preventívnej prehliadke. Dvojnásobne by ste na ne mali dbať, ak spadáte do rizikovej skupiny. „Preventívky sú bezplatné a bezbolestné a lekár pri nich okrem už spomínaného ochorenia obličiek dokáže posúdiť aj iné nebezpečné diagnózy, ktoré vedú k ochoreniu obličiek, ako sú diabetes a vysoký krvný tlak, no tiež anémia (chudokrvnosť), zvýšená hladina cholesterolu, poruchy funkcie pečene, rakovina hrubého čreva a ďalšie zdravotné komplikácie,“ hovorí docent Demeš.

Vyšetrenie nebolí a nič vás nestojí

Ak máte diabetes, problémy so srdcom či sa liečite na vysoký krvný tlak alebo máte rodinnú predispozíciu, v rámci preventívnej prehliadky požiadajte svojho lekára aj o vyšetrenie obličiek. Odborník najskôr vyšetrí váš moč a keď sa v ňom objavia bielkoviny či iné látky, ktoré v zdravom moči nemajú čo hľadať, pôjdete k nefrológovi na sono obličiek. Následná liečba závisí od stupňa poškodenia obličiek a určí ju špecialista. Viac sa o chronickom ochorení obličiek dozviete na www.vysetrioblicky.sk.

20 komentárov

  • Komentár Εξατομικευμένα προγράμματα για κάθε στόχο %AM, %01 %305 %2025 %06:%nov napísal Εξατομικευμένα προγράμματα για κάθε στόχο

    It’s true that utilizing certain steroids in small quantities underneath medical supervision won’t hurt you.
    However, using large quantities of anabolic steroids for a protracted time
    period can do you actual hurt. Athletes take human progress hormone, additionally called somatotropin, to build extra muscle and do better at their sports activities.

    A Home Workplace licence is required for importation and exportation of
    anabolic steroids, besides in cases of small quantities for reliable functions.
    The findings suggest that continual high-dose use of anabolic
    steroids induces morphological mind changes, together with
    cortical atrophy and amygdala hypertrophy
    (Bertozzi et al., 2019). Moreover, extended use of anabolic steroids
    has been proven to modulate the expression of serotonin receptors, leading to a discount in serotonin activity within the
    CNS (Seo et al., 2008). This alteration in serotonin signaling also impacts the release of
    different neurotransmitters, together with acetylcholine in the hippocampus and dopamine in the
    prefrontal cortex. These changes in neurotransmitter dynamics are implicated within the manifestation of aggressive behavior (Bertozzi et
    al., 2018). A new examine has discovered that long-term use of anabolic steroids can result in vital mind structural changes and cognitive impairment.
    The analysis team used scans to match the brains of folks who had used anabolic
    steroids for a minimum of two years with those who had by no
    means taken them.
    Strength features of about 5–20% of the initial energy and increments of 2–5kg body weight, which may be attributed to a rise of
    the lean physique mass, have been observed. Although AAS administration might have an effect on erythropoiesis and
    blood haemoglobin concentrations, no effect on endurance performance
    was observed. Little knowledge in regards to the effects of AAS on metabolic responses
    throughout train training and restoration are available
    and, therefore, don't permit firm conclusions.
    It is accepted that the administration of anabolic steroids to wholesome girls
    and youngsters has an anabolic impact, and that with the virilizing effects, there is a acquire in muscle mass and power.
    Nonetheless, for many years, it was tough to show conclusively that the administration of these
    steroids had a myotrophic effect in healthy young sportsmen, as mentioned by Ryan (1976) (see the part ‘Anabolic steroids as
    efficiency enhancers in sport'). It was subsequently
    reasoned that any potential myotrophic effect from administration of anabolic steroids to eugonadal men could presumably be through an anticatabolic mechanism quite than a direct anabolic effect.


    Testosterone is predominantly administered via intramuscular injection; nonetheless,
    it is also obtainable orally (known as testosterone undecanoate).
    Dianabol can also be liver toxic, being a C-17 alpha-alkylated
    steroid, thus having to move by way of the liver in order to become energetic.
    Any excess fluid gained from Anadrol shall be flushed out when a cycle finishes and estrogen levels return to normal.

    Anadrol can be some of the highly effective compounds
    for enhancing power, making it very fashionable amongst strongmen and powerlifters, in our
    expertise.
    Since a big majority of AAS users were boys (see Johnston et al., 2006, p.

    243), lifetime AAS use for boys alone on this study
    was likely about 5%. In 1991, AAS were included
    for the primary time on the National Household Survey (NHS) of drug
    use. This survey produced decrease estimates of AAS use than the nameless questionnaire
    studies, for causes that we now have discussed elsewhere (Kanayama et al., 2007).
    However even by this extra conservative estimate, practically 1,000,000 American men had used AAS
    by 1991 (SAMHSA, 1991; Yesalis et al., 1993). In 1990,
    the Usa Congress passed the Steroid Trafficking Act (One Hundred First Congress, 1990), acknowledging that AAS use had arisen as an essential
    substance use problem within the Usa. Also by the early 1990s, population studies began to document widespread AAS use among
    college students in the United Kingdom (Williamson, 1993), South Africa
    (Schwellnus et al., 1992), and Scandinavia (Nilsson, 1995).

    This will be important when you’re utilizing a quantity of sluggish acting (long ester) steroids that have long
    half-lives. Without a kickstart or frontloading, you will be ready weeks to see outcomes with steroids like Deca-Durabolin and
    Equipoise, that are well-known for his or her long half-lives.

    The elimination half-life of each steroid you intend to make
    use of in your cycle will decide how typically you want to take your
    dosage, whether or not that be your entire weekly dosage or, in some circumstances, splitting the dose into multiple administrations every week.
    So, you'll be able to see the importance of familiarity with
    each compound’s half-life, even if you’re going with only a single
    compound cycle. For performance enhancement, we will rarely wish
    to wait until the steroid’s half-life is reaching a close point, as that’s when you’ll experience a drop in blood
    levels of the steroid and a decline in consistent efficiency effects.
    Nonetheless, the method of esterification (attachment of an ester) is maybe probably the most crucial
    factor in a steroid’s half-life. The bonded ester controls the speed at which the hormone is launched into
    your body after injection.
    Anabolic steroids (also generally recognized as anabolic-androgenic steroids) are
    a unique kind of drug and illegal in most international locations
    and not using a written prescription from a pharmacist.
    These medication mimic the intercourse hormone testosterone and are well-known for
    being misused by some athletes to achieve an edge over their opponents.
    During the course of therapy with anabolic steroids, healthcare professionals should regularly
    acquire and monitor sure parameters. These embody the patient’s lipid profile, hepatic function exams,
    hemoglobin, and hematocrit levels. It is really helpful to assess these parameters at
    3 to 6 months after initiation of therapy and then yearly.

    As the primary large wave of former AAS customers now
    strikes into middle age, it will be essential to obtain extra systematic data on the long-term
    psychiatric and medical penalties of this type of substance abuse.
    To maximize benefits, corticosteroids are prescribed within the lowest attainable dose over the shortest time frame to attain the
    best possible consequence. For those who are having hassle with erectile dysfunction, one
    of the only ways to keep away from this from occurring is
    by either going with different AAS or stopping the medication.

  • Komentár blackcoin.co %AM, %10 %196 %2025 %03:%aug napísal blackcoin.co

    rides

  • Komentár none %AM, %15 %425 %2025 %09:%jún napísal none

    70918248

  • Komentár atachin.Es %PM, %14 %566 %2025 %12:%jún napísal atachin.Es

    70918248

  • Komentár Edgar %AM, %14 %326 %2025 %06:%jún napísal Edgar

    70918248

  • Komentár lozanoinc.com %PM, %12 %619 %2025 %13:%jún napísal lozanoinc.com

    70918248

  • Komentár Are Steroids a stimulant %AM, %12 %272 %2025 %05:%jún napísal Are Steroids a stimulant

    70918248

  • Komentár https://tanztheater-erfurt.de %PM, %28 %868 %2025 %19:%máj napísal https://tanztheater-erfurt.de

    Steroids similar to prednisolone can scale back inflammation within the lungs however have extreme side-effects such as diabetes and osteoporosis.

    Moreover, many sufferers 'fail' remedy and want repeated courses of
    steroids, re-hospitalisation or die within ninety days.
    Selecting a legal steroid comes down to which brand delivers probably the most advantages you’re looking for, whether or not it's a testosterone booster or
    a post-cycle formulation. There are many similar
    pure steroids out there, so search for ones with ample testosterone assist to advertise muscle mass and energy.
    Their constructions have been elucidated by in depth nuclear mangnetic resonance, spectrum evaluation and single crystal X-ray
    diffraction analysis.
    This also permits you to create effective stacks
    with synergistic SARMs (see additional on this information for more details).
    We further investigated the potential anti-inflammatory effects of SCA and SCB compounds by evaluating
    gene and protein expression of NFκB target cytokines in HaCaT cells stimulated with TNFα.
    three, TNFα stimulation induced a robust nuclear accumulation of p65 NF-κB subunit in HaCaT
    cells. Similarly, pretreatment of HaCaT cells with betamethasone, a extensively known steroidal anti-inflammatory agent, solely partly prevented TNFα-mediated p65 activation (Fig.
    3). As anticipated, vehicle-treated (DMSO) and untreated HaCaT cells displayed
    the immunofluorescence staining of p65 mostly restricted in the cytoplasm (Fig.
    3). Regardless Of their undoubted efficacy in treating varied pathologies, corticosteroids have varied unwanted facet effects that limit
    their use.
    The most important distinction between SARMs and steroids is what we can name their
    mechanism of motion. In different words, how they work within the physique
    to promote muscle development, performance enhancement, fats loss, and different results.
    The relatively unknown nature of SARMs makes every person’s experience an experiment – and it’s up to you
    should you select to take that risk. What is usually accepted
    is that SARMs have milder unwanted side effects
    than anabolic steroids and that some side effects attributable to
    steroids don’t occur at all with SARMs or are in any other case
    gentle. There are other androgenic-type unwanted effects that some SARMs may cause, other than hair loss.
    However they may primarily solely have an effect on you if you’re prone already,
    and an enormous quantity of SARM customers don’t experience
    noticeable androgenic results in any respect.

    Another very critical concern many people have about folks using SARMs is whether or not
    they have an result on cardiovascular health and if they can probably even lead to coronary
    heart attacks. In 2017, the US FDA issued a warning about SARMs
    and stated that they could enhance the danger of heart attack and stroke31.
    Chopping and contest prep cycles can profit from either Proviron or S-4, but if you want to increase energy and muscle
    gains, the S-4 is the higher choice. Proviron is a poor muscle builder, however on the flip aspect,
    it’s the stronger of the two in the aesthetics department.
    After all, that’s certainly one of their primary promoting factors in the bodybuilding community!

    Getting your heart pumping quick for no less than minutes will greatly profit your cardiovascular well being.
    SARMs like YK11 and S23 are noted for their suppressive qualities.
    Some SARMs won’t even require PCT, while the more suppressive ones
    require a testosterone base on the cycle and 4 weeks of
    PCT afterward.
    Despite excessive efficacy of steroid formulations and dietary restrictions,
    a considerable proportion of sufferers do not achieve or
    maintain clinico-histological remission, particularly in the long-term.
    Biological agents could be an efficient therapy various, anti-IL13 and anti-IL4r
    antibodies are most promising with section 2 knowledge thus far.

    A Number Of newer targets have been identified and are at present tested in clinical trials such as the AT1 receptor
    (losartan) or Siglec-8 (anti-Siglec-8). This ends in larger inhibitory tone onto VB from GABAergic nRT inputs.

    Hyperpolarization of VB neurons leads to activation of T-channels and hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, resulting
    in burst firing of motion potentials, characteristic of delta activity117.

    There’s no reason why you won’t maintain close to one hundred pc of your existing muscle
    with this stack. Some customers will find excellent vascularity and pump with Ostarine,
    while others will see minimal results. Cardarine will make
    your body use fat as gasoline, resulting in probably very quick fat-burning quickly
    after beginning this cycle.
    Though the one presented is an in vitro preliminary research,
    these outcomes recommend a decrease efficacy of SCA and
    SCB in activating the glucocorticoid receptors in respect to classical corticosteroids.
    This promising state of affairs, nonetheless, must be confirmed in an additional in depth in vivo examine.
    In the mid Seventies, there was a push to maneuver away from
    the default use of inhalant anesthetics since they are recognized to trigger profound respiratory and cardiovascular
    melancholy. CT1341’s massive therapeutic index and lack of cumulative effects helped pave the means in which for the utilization of intravenous anesthetics as maintenance agents for total intravenous anesthesia (TIVA)15.
    Nonetheless, as CT1341 became administered for longer durations, one serious
    side-effect became extra evident. Several patients experienced
    anaphylactic reactions to the anesthetic which were typically lethal.
    As it turned out, the anaphylaxis was caused by the car, Cremophor EL16,17.

  • Komentár alllifesciences.com %PM, %18 %606 %2025 %13:%máj napísal alllifesciences.com

    70918248

  • Komentár Anabolic Steroid forums %AM, %18 %188 %2025 %03:%máj napísal Anabolic Steroid forums

    70918248